Summary of Position
Quiver Bioscience is seeking a highly motivated Research Associate (RA) to develop and execute cutting-edge optogenetic assays and high throughput screens of neuronal function. As a part of the Quiver Bioscience R&D team, the RA will work closely with other RAs and Scientists in a high-energy, scientifically rigorous
Responsibilities and Duties
- Assist with culture of human iPS cell lines and their conversion into different types of neurons.
- Maintain rodent primary and human iPS cell-derived neuronal cultures for all-optical electrophysiology recordings.
- Carry out high throughput optical electrophysiology/fluorescence microscopy recordings on Quiver’s custom-built, highly automated fluorescence microscopes.
- Assist with large-scale data collection of neuronal function for machine learning.
- Manage and process datasets through our data analysis pipeline.
- Characterize cultured neurons using molecular biology assays (RNA/DNA prep and qPCR).
- Maintain a meticulous and up-to-date record of experimental procedures and results.
- Assist in maintenance of the cell culture facility and microscopes.
Minimum Qualifications Required
- A Bachelor’s or master’s degree in biology, engineering, chemistry, or a related field.
- A minimum of one year of hands-on experience in cell culture and basic molecular biology methods (DNA/RNA preparations and PCR/qPCR)
- A minimum of one year of hands-on experience in fluorescence microscopy.
- Ability to work independently and in cross-functional teams.
Additional Qualifications Desired
- Proficiency with MATLAB, Python, or other programming language is a plus.
- Experience with human iPS cells and neuronal cultures is a plus.
- Experience with 96/384-well cultures and automated liquid handling workflows.
- Experience in electrophysiology.
- Flexibility to work alternative hours for optimal instrument scheduling.