Charles Berde, M.D. Ph.D.

Charles Berde, M.D. Ph.D. is Senior Associate and the Sara Page Mayo Chair in Pain Medicine, in the Department of Anesthesiology, Critical Care and Pain Medicine at Boston Children’s Hospital (BCH) and Professor of Anesthesia (Pediatrics) at Harvard Medical School. He completed an MD and PhD in Biophysics at Stanford University, residency in pediatrics at BCH, residency in anesthesiology at Massachusetts General Hospital and fellowship in Pediatric Anesthesiology at BCH. Dr. Berde’s clinical expertise is in the treatment of acute and chronic pain, especially neuropathic pain. He is the co- founder of the Pain Treatment Center at BCH. Dr. Berde has directed clinical trials of analgesics and local anesthetics in children and adolescents and has served on two FDA consensus committees on design of pediatric analgesic trials. He has been involved in multiple investigator-sponsored and industry-sponsored intrathecally delivered ASO clinical trials conducted at BCH for CNS indications. His translational research focuses on the clinical development of novel prolonged duration local anesthetics. Dr. Berde developed an infant rat model for spinal anesthesia, to foster modeling of rodent-to-human scaling for spinal anesthesia. His clinical team at BCH has established strong relationships with patient communities affected by chronic pain disorders, including erythromelalgia and small fiber neuropathy. Dr. Berde and his collaborators have established an erythromelalgia gene discovery program at BCH through the Manton Center for Orphan Diseases. His team has also launched a 32-center collaboration and registry around erythromelalgia in children and young adults.